CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Interleukin-1 receptor-associated kinase 1 (Predicted)

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P51617
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P51617
IRAK1_HUMAN
Homo sapiens
Interleukin-1 receptor-associated kinase 1

PDB Structure

PDB 6BFN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human IRAK1.
Wang, L., Qiao, Q., Ferrao, R., Shen, C., Hatcher, J.M., Buhrlage, S.J., Gray, N.S., Wu, H.
Proc. Natl. Acad. Sci. U.S.A.
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