CATH Domain 6b2tB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.47	Peroxisomal Thiolase; Chain A, domain 1
	3.40.47.10	Thiolase/Chalcone synthase

Domain Context

CATH Clusters

Superfamily	3.40.47.10
Functional Family	3-oxoacyl-ACP synthase III

Enzyme Information

2.3.3.20

Acyl-CoA:acyl-CoA alkyltransferase.

based on mapping to UniProt Q8PDX2

2 an acyl-CoA + H(2)O = a (2R)-2-alkyl-3-oxoalkanoate + 2 CoA.

-!- The enzyme, found in certain bacterial species, catalyzes a head- to-head non-decarboxylative Claisen condensation of two acyl-CoA molecules, resulting in formation of a 2-alkyl-3-oxoalkanoic acid. -!- It is part of a pathway for the production of olefins.

UniProtKB Entries (1)

Q8PDX2

OLEA_XANCP

Xanthomonas campestris pv. campestris str. ATCC 33913

Acyl-CoA:acyl-CoA alkyltransferase

PDB Structure

PDB	6B2T
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. Jensen, M.R., Goblirsch, B.R., Esler, M.A., Christenson, J.K., Mohamed, F.A., Wackett, L.P., Wilmot, C.M. FEBS Lett.