CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.80 | Rhinovirus 14, subunit 4 |
|
4.10.80.40 | succinate dehydrogenase protein domain |
Domain Context
CATH Clusters
| Superfamily | succinate dehydrogenase protein domain |
| Functional Family | Fumarate reductase flavoprotein subunit |
Enzyme Information
| 1.3.5.4 |
Fumarate reductase (quinol).
based on mapping to UniProt P00363
Succinate + a quinone = fumarate + a quinol.
-!- The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. -!- The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, to which it is closely related.
|
UniProtKB Entries (3)
| P00363 |
FRDA_ECOLI
Escherichia coli K-12
Fumarate reductase flavoprotein subunit
|
| B7MKV8 |
FRDD_ECO45
Escherichia coli S88
Fumarate reductase subunit D
|
| P0AC49 |
FRDB_ECO57
Escherichia coli O157:H7
Fumarate reductase iron-sulfur subunit
|
PDB Structure
| PDB | 6AWF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement.
J. Struct. Biol.
|
