CATH Domain 5wewH00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.180	2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1
	3.10.180.10	2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Domain Context

CATH Clusters

Superfamily	2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1
Functional Family

Enzyme Information

UniProtKB Entries (1)

W8UNW6_KLEPN

Klebsiella pneumoniae 30684/NJST258_2

Fosfomycin resistance protein

PDB Structure

PDB	5WEW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens. Tomich, A.D., Klontz, E.H., Deredge, D., Barnard, J.P., McElheny, C.L., Eshbach, M.L., Weisz, O.A., Wintrode, P., Doi, Y., Sundberg, E.J., Sluis-Cremer, N. Antimicrob. Agents Chemother.