CATH Domain 5w97a00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.210	Cytochrome C Oxidase; Chain A
	1.20.210.10	Cytochrome c oxidase-like, subunit I domain

Domain Context

CATH Clusters

Superfamily	Cytochrome c oxidase-like, subunit I domain
Functional Family	Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1

Cytochrome-c oxidase.

based on mapping to UniProt P00396

4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.

-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

P00430

COX7C_BOVIN

Bos taurus

Cytochrome c oxidase subunit 7C, mitochondrial

PDB Structure

PDB	5W97
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Ishigami, I., Zatsepin, N.A., Hikita, M., Conrad, C.E., Nelson, G., Coe, J.D., Basu, S., Grant, T.D., Seaberg, M.H., Sierra, R.G., Hunter, M.S., Fromme, P., Fromme, R., Yeh, S.R., Rousseau, D.L. Proc. Natl. Acad. Sci. U.S.A.