CATH Domain 5uqeC02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family	glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2

Glutaminase.

based on mapping to UniProt O94925

L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

GLSK_HUMAN

Homo sapiens

Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB	5UQE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. Pasquali, C.C., Islam, Z., Adamoski, D., Ferreira, I.M., Righeto, R.D., Bettini, J., Portugal, R.V., Yue, W.W., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B. J. Biol. Chem.