CATH Domain 5npgA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.160	Double Stranded RNA Binding Domain
	3.30.160.20

Domain Context

CATH Clusters

Superfamily	3.30.160.20
Functional Family	RISC-loading complex subunit TARBP2

Enzyme Information

UniProtKB Entries (1)

X2J5X6_DROME

Drosophila melanogaster

Loquacious, isoform F

PDB Structure

PDB	5NPG
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference. Tants, J.N., Fesser, S., Kern, T., Stehle, R., Geerlof, A., Wunderlich, C., Juen, M., Hartlmuller, C., Bottcher, R., Kunzelmann, S., Lange, O., Kreutz, C., Forstemann, K., Sattler, M. Nucleic Acids Res.