CATH Domain 5mnuB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6

Beta-lactamase.

based on mapping to UniProt P14489

A beta-lactam + H(2)O = a substituted beta-amino acid.

-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P14489

BLO10_PSEAI

Pseudomonas aeruginosa

Beta-lactamase OXA-10

PDB Structure

PDB	5MNU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	(13)C-Carbamylation as a mechanistic probe for the inhibition of class D beta-lactamases by avibactam and halide ions. Lohans, C.T., Wang, D.Y., Jorgensen, C., Cahill, S.T., Clifton, I.J., McDonough, M.A., Oswin, H.P., Spencer, J., Domene, C., Claridge, T.D.W., Brem, J., Schofield, C.J. Org. Biomol. Chem.