CATH Classification

Domain Context

CATH Clusters

Superfamily CBS-domain
Functional Family

Enzyme Information

7.6.2.9
ABC-type quaternary amine transporter.
based on mapping to UniProt Q9KHT9
ATP + H(2)O + quaternary amine-[quaternary amine-binding protein](Side 1) = ADP + phosphate + quaternary amine(Side 2) + [quaternary amine-binding protein](Side 1).
-!- An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. -!- Does not undergo phosphorylation during the transport process. -!- A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of quaternary amine derivatives. -!- Formerly EC 3.6.3.32.

UniProtKB Entries (1)

Q9KHT9
OPUCA_LISMN
Listeria monocytogenes
Carnitine transport ATP-binding protein OpuCA

PDB Structure

PDB 5KS7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.
Huynh, T.N., Choi, P.H., Sureka, K., Ledvina, H.E., Campillo, J., Tong, L., Woodward, J.J.
Mol.Microbiol.
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