CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.50 | Alpha/alpha barrel |
|
1.50.10 | Glycosyltransferase |
|
1.50.10.10 |
Domain Context
CATH Clusters
| Superfamily | 1.50.10.10 |
| Functional Family | alpha-1,2-Mannosidase |
Enzyme Information
| 3.2.1.113 |
Mannosyl-oligosaccharide 1,2-alpha-mannosidase.
based on mapping to UniProt Q9UKM7
Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
-!- Involved in the synthesis of glycoproteins.
|
UniProtKB Entries (1)
| Q9UKM7 |
MA1B1_HUMAN
Homo sapiens
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
|
PDB Structure
| PDB | 5KIJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Proc. Natl. Acad. Sci. U.S.A.
|
