CATH Domain 5jsnB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.132	Topoisomerase I; Chain A, domain 4
	1.10.132.20	Ribosome-recycling factor

Domain Context

CATH Clusters

Superfamily	Ribosome-recycling factor
Functional Family

Enzyme Information

UniProtKB Entries (1)

BCL2_HUMAN

Homo sapiens

Apoptosis regulator Bcl-2

PDB Structure

PDB	5JSN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Berger, S., Procko, E., Margineantu, D., Lee, E.F., Shen, B.W., Zelter, A., Silva, D.A., Chawla, K., Herold, M.J., Garnier, J.M., Johnson, R., MacCoss, M.J., Lessene, G., Davis, T.N., Stayton, P.S., Stoddard, B.L., Fairlie, W.D., Hockenbery, D.M., Baker, D. Elife