CATH Domain 5iq9A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.10	Immunoglobulins

Domain Context

CATH Clusters

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

Q1HSF8_9HIV1

Human immunodeficiency virus 1

Envelope glycoprotein gp160

PDB Structure

PDB	5IQ9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. Kwon, Y.D., Georgiev, I.S., Ofek, G., Zhang, B., Asokan, M., Bailer, R.T., Bao, A., Caruso, W., Chen, X., Choe, M., Druz, A., Ko, S.Y., Louder, M.K., McKee, K., O'Dell, S., Pegu, A., Rudicell, R.S., Shi, W., Wang, K., Yang, Y., Alger, M., Bender, M.F., Carlton, K., Cooper, J.W., Blinn, J., Eudailey, J., Lloyd, K., Parks, R., Alam, S.M., Haynes, B.F., Padte, N.N., Yu, J., Ho, D.D., Huang, J., Connors, M., Schwartz, R.M., Mascola, J.R., Kwong, P.D. J.Virol.