CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.120 | Four Helix Bundle (Hemerythrin (Met), subunit A) |
|
1.20.120.350 | Voltage-gated potassium channels. Chain C |
Domain Context
CATH Clusters
| Superfamily | Voltage-gated potassium channels. Chain C |
| Functional Family | Sodium channel protein |
Enzyme Information
UniProtKB Entries (2)
| Q15858 |
SCN9A_HUMAN
Homo sapiens
Sodium channel protein type 9 subunit alpha
|
| A8EVM5 |
A8EVM5_ARCB4
Arcobacter butzleri RM4018
Ion transport protein
|
PDB Structure
| PDB | 5EK0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist.
Science
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