CATH Domain 5e80A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.50	Coagulation Factor XIII; Chain A, domain 1
	2.70.50.40	GMP phosphodiesterase, delta subunit

Domain Context

CATH Clusters

Superfamily	GMP phosphodiesterase, delta subunit
Functional Family	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

Enzyme Information

UniProtKB Entries (1)

PDE6D_HUMAN

Homo sapiens

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta

PDB Structure

PDB	5E80
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of pyrazolopyridazinones as PDE delta inhibitors. Papke, B., Murarka, S., Vogel, H.A., Martin-Gago, P., Kovacevic, M., Truxius, D.C., Fansa, E.K., Ismail, S., Zimmermann, G., Heinelt, K., Schultz-Fademrecht, C., Al Saabi, A., Baumann, M., Nussbaumer, P., Wittinghofer, A., Waldmann, H., Bastiaens, P.I. Nat Commun