CATH Domain 4yylA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.91	Restriction Endonuclease
	3.40.91.90	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Domain Context

CATH Clusters

Superfamily	Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Functional Family

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt P03433

UniProtKB Entries (1)

PA_I34A1

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

Polymerase acidic protein

PDB Structure

PDB	4YYL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase Fudo, S., Yamamoto, N., Nukaga, M., Odagiri, T., Tashiro, M., Neya, S., Hoshino, T. Bioorg.Med.Chem.