CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidase S8/S53 domain
Functional Family

Enzyme Information

3.4.21.25
Cucumisin.
based on mapping to UniProt Q39547
Hydrolysis of proteins with broad specificity.
-!- From the sarcocarp of the musk melon (Cucumis melo). -!- Other endopeptidases from plants, which are less well characterized but presumably of serine-type, include euphorbain from Euphorbia cerifera, solanain from horse-nettle Solanum elaeagnifolium, hurain from Hura crepitans and tabernamontanain from Tabernamontana grandiflora. -!- Belongs to peptidase family S8.

UniProtKB Entries (1)

Q39547
CUCM1_CUCME
Cucumis melo
Cucumisin

PDB Structure

PDB 4YN3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of cucumisin protease activity regulation by its propeptide
Sotokawauchi, A., Kato-Murayama, M., Murayama, K., Hosaka, T., Maeda, I., Onjo, M., Ohsawa, N., Kato, D.I., Arima, K., Shirouzu, M.
J. Biochem.
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