CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent dethiobiotin synthetase BioD

Enzyme Information

6.3.3.3
Dethiobiotin synthase.
based on mapping to UniProt A5U2S7
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
-!- CTP has half the activity of ATP.

UniProtKB Entries (1)

A5U2S7
BIOD_MYCTA
Mycobacterium tuberculosis H37Ra
ATP-dependent dethiobiotin synthetase BioD

PDB Structure

PDB 4WOP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase.
Salaemae, W., Yap, M.Y., Wegener, K.L., Booker, G.W., Wilce, M.C., Polyak, S.W.
Tuberculosis (Edinb)
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