CATH Domain 4uu9C00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.91	Influenza Virus Matrix Protein; Chain A, domain 1
	1.20.91.20	Anaphylotoxins (complement system)

Domain Context

CATH Clusters

Superfamily	Anaphylotoxins (complement system)
Functional Family	Complement C5

Enzyme Information

UniProtKB Entries (1)

CO5_HUMAN

Homo sapiens

Complement C5

PDB Structure

PDB	4UU9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors. Colley, C.S., Popovic, B., Sridharan, S., Debreczeni, J.E., Hargeaves, D., Fung, M., An, L.L., Edwards, B., Arnold, J., England, E., Eghobamien, L., Sivars, U., Flavell, L., Renshaw, J., Wickson, K., Warrener, P., Zha, J., Bonnell, J., Woods, R., Wilkinson, T., Dobson, C., Vaughan, T.J. MAbs