CATH Domain 4utzB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1220	TPP-binding domain

Domain Context

CATH Clusters

Superfamily	TPP-binding domain
Functional Family	NAD-dependent protein deacylase 1

Enzyme Information

3.5.1.-

In linear amides.

based on mapping to UniProt Q6DHI5

UniProtKB Entries (2)

P31327	CPSM_HUMAN Homo sapiens Carbamoyl-phosphate synthase [ammonia], mitochondrial
Q6DHI5	SIR5_DANRE Danio rerio NAD-dependent protein deacylase sirtuin-5, mitochondrial

PDB Structure

PDB	4UTZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors. Roessler, C., Nowak, T., Pannek, M., Gertz, M., Nguyen, G.T., Scharfe, M., Born, I., Sippl, W., Steegborn, C., Schutkowski, M. Angew.Chem.Int.Ed.Engl.