CATH Domain 4tydA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

Q0ZNA6_9HEPC

Hepacivirus C

NS3 protease

PDB Structure

PDB	4TYD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease. Parsy, C., Alexandre, F.R., Brandt, G., Caillet, C., Cappelle, S., Chaves, D., Convard, T., Derock, M., Gloux, D., Griffon, Y., Lallos, L., Leroy, F., Liuzzi, M., Loi, A.G., Moulat, L., Musiu, C., Rahali, H., Roques, V., Seifer, M., Standring, D., Surleraux, D. Bioorg.Med.Chem.Lett.