CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.390 | Neutral Protease; domain 2 | |
1.10.390.10 | Neutral Protease Domain 2 |
Domain Context
CATH Clusters
Superfamily | Neutral Protease Domain 2 |
Functional Family | Aminopeptidase N |
Enzyme Information
UniProtKB Entries (1)
Q9JYV4 |
Q9JYV4_NEIMB
Neisseria meningitidis MC58
Aminopeptidase N
|
PDB Structure
PDB | 4QPE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.
J.Med.Chem.
|