CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.200 |
Domain Context
CATH Clusters
| Superfamily | 2.60.120.200 |
| Functional Family |
Enzyme Information
| 4.2.2.3 |
Mannuronate-specific alginate lyase.
based on mapping to UniProt Q59478
Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy- alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.
-!- The enzyme catalyzes the degradation of alginate by a beta- elimination reaction. -!- It cleaves the (1->4) bond between beta-D-mannuronate and either alpha-L-guluronate or beta-D-mannuronate, generating oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non- reducing ends and beta-D-mannuronate at the reducing end. -!- Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to four residues, with preference for shorter products. -!- Cf. EC 4.2.2.11. -!- Formerly EC 4.2.99.4.
|
UniProtKB Entries (1)
| Q59478 |
ALYA_KLEPN
Klebsiella pneumoniae
Alginate lyase
|
PDB Structure
| PDB | 4OZX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the alginate lyase from Klebsiella pneumoniae
To be published
|
