CATH Domain 4n90R02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.50	Tumor Necrosis Factor Receptor, subunit A; domain 2
	2.10.50.10	Tumor Necrosis Factor Receptor, subunit A, domain 2

Domain Context

CATH Clusters

Superfamily	Tumor Necrosis Factor Receptor, subunit A, domain 2
Functional Family	Tumor necrosis factor receptor superfamily member 6

Enzyme Information

UniProtKB Entries (1)

TNF10_HUMAN

Homo sapiens

Tumor necrosis factor ligand superfamily member 10

PDB Structure

PDB	4N90
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity. Graves, J.D., Kordich, J.J., Huang, T.H., Piasecki, J., Bush, T.L., Sullivan, T., Foltz, I.N., Chang, W., Douangpanya, H., Dang, T., O'Neill, J.W., Mallari, R., Zhao, X., Branstetter, D.G., Rossi, J.M., Long, A.M., Huang, X., Holland, P.M. Cancer Cell