CATH Domain 4miaB02

Superfamily
Functional Family	-

PDB	4MIA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of N-[4-[6-tert-butyl-5-methoxy-8-(6-methoxy-2-oxo-1H-pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a potent inhibitor of the hepatitis C virus NS5B polymerase. Talamas, F.X., Abbot, S.C., Anand, S., Brameld, K.A., Carter, D.S., Chen, J., Davis, D., de Vicente, J., Fung, A.D., Gong, L., Harris, S.F., Inbar, P., Labadie, S.S., Lee, E.K., Lemoine, R., Le Pogam, S., Leveque, V., Li, J., McIntosh, J., Najera, I., Park, J., Railkar, A., Rajyaguru, S., Sangi, M., Schoenfeld, R.C., Staben, L.R., Tan, Y., Taygerly, J.P., Villasenor, A.G., Weller, P.E. J.Med.Chem.