CATH Domain 4lqcA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10140	Toll/interleukin-1 receptor homology (TIR) domain

Domain Context

CATH Clusters

Superfamily	Toll/interleukin-1 receptor homology (TIR) domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q8YF53_BRUME

Brucella melitensis bv. 1 str. 16M

Uncharacterized protein

PDB Structure

PDB	4LQC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry. Snyder, G.A., Deredge, D., Waldhuber, A., Fresquez, T., Wilkins, D.Z., Smith, P.T., Durr, S., Cirl, C., Jiang, J., Jennings, W., Luchetti, T., Snyder, N., Sundberg, E.J., Wintrode, P., Miethke, T., Xiao, T.S. J.Biol.Chem.