CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.2350 | Pseudouridine synthase |
|
3.30.2350.10 | Pseudouridine synthase |
Domain Context
CATH Clusters
| Superfamily | Pseudouridine synthase |
| Functional Family | Pseudouridine synthase |
Enzyme Information
| 5.4.99.22 |
23S rRNA pseudouridine(2605) synthase.
based on mapping to UniProt P37765
23S rRNA uridine(2605) = 23S rRNA pseudouridine(2605).
-!- Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine.
|
UniProtKB Entries (1)
| P37765 |
RLUB_ECOLI
Escherichia coli K-12
Ribosomal large subunit pseudouridine synthase B
|
PDB Structure
| PDB | 4LGT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs.
Nucleic Acids Res.
|
