CATH Domain 4jy4B02

Superfamily	Immunoglobulins
Functional Family	Immunoglobulin heavy constant gamma 1

PDB	4JY4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Julien, J.P., Sok, D., Khayat, R., Lee, J.H., Doores, K.J., Walker, L.M., Ramos, A., Diwanji, D.C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R.S., Stanfield, R.L., McBride, R., Marozsan, A.J., Paulson, J.C., Sanders, R.W., Moore, J.P., Burton, D.R., Poignard, P., Ward, A.B., Wilson, I.A. Plos Pathog.