CATH Domain 4bqsA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Shikimate kinase

Enzyme Information

2.7.1.71

Shikimate kinase.

based on mapping to UniProt P9WPY2

ATP + shikimate = ADP + shikimate 3-phosphate.

UniProtKB Entries (1)

AROK_MYCTO

Mycobacterium tuberculosis CDC1551

Shikimate kinase

PDB Structure

PDB	4BQS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mycobacterium tuberculosis shikimate kinase inhibitors: design and simulation studies of the catalytic turnover. Blanco, B., Prado, V., Lence, E., Otero, J.M., Garcia-Doval, C., van Raaij, M.J., Llamas-Saiz, A.L., Lamb, H., Hawkins, A.R., Gonzalez-Bello, C. J. Am. Chem. Soc.