CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1580 | Nucleoside phosphorylase domain |
Domain Context
CATH Clusters
Superfamily | Nucleoside phosphorylase domain |
Functional Family | Aminodeoxyfutalosine nucleosidase |
Enzyme Information
3.2.2.30 |
Aminodeoxyfutalosine nucleosidase.
based on mapping to UniProt O24915
6-amino-6-deoxyfutalosine + H(2)O = dehypoxanthine futalosine + adenine.
-!- The enzyme, found in several bacterial species, catalyzes a step in a modified futalosine pathway for menaquinone biosynthesis. -!- While the enzyme from some organisms also has the activity of EC 3.2.2.9 the enzyme from Chlamydia trachomatis is specific for 6-amino-6-deoxyfutalosine.
|
3.2.2.9 |
Adenosylhomocysteine nucleosidase.
based on mapping to UniProt O24915
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.
|
UniProtKB Entries (1)
O24915 |
MQMTN_HELPY
Helicobacter pylori 26695
Aminodeoxyfutalosine nucleosidase
|
PDB Structure
PDB | 4BMY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D
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