CATH Domain 4a2xA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.150	Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A
	2.170.150.30	RIG-I-like receptor, C-terminal regulatory domain

Domain Context

CATH Clusters

Superfamily	RIG-I-like receptor, C-terminal regulatory domain
Functional Family	Probable ATP-dependent RNA helicase DDX58

Enzyme Information

UniProtKB Entries (1)

D3TI84_ANAPL

Anas platyrhynchos

Retinoic acid inducible protein I transcript variant 2

PDB Structure

PDB	4A2X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Kowalinski, E., Lunardi, T., McCarthy, A.A., Louber, J., Brunel, J., Grigorov, B., Gerlier, D., Cusack, S. Cell