CATH Domain 3t3pB01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1680	ligand-binding face of the semaphorins, domain 2
	3.30.1680.10	ligand-binding face of the semaphorins, domain 2

Domain Context

CATH Clusters

Superfamily	ligand-binding face of the semaphorins, domain 2
Functional Family	Integrin beta

Enzyme Information

UniProtKB Entries (1)

ITA2B_HUMAN

Homo sapiens

Integrin alpha-IIb

PDB Structure

PDB	3T3P
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS Zhu, J., Choi, W.S., McCoy, J.G., Negri, A., Zhu, J., Naini, S., Li, J., Shen, M., Huang, W., Bougie, D., Rasmussen, M., Aster, R., Thomas, C.J., Filizola, M., Springer, T.A., Coller, B.S. Sci Transl Med