CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

P08637
FCG3A_HUMAN
Homo sapiens
Low affinity immunoglobulin gamma Fc region receptor III-A

PDB Structure

PDB 3SGK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose.
Ferrara, C., Grau, S., Jager, C., Sondermann, P., Brunker, P., Waldhauer, I., Hennig, M., Ruf, A., Rufer, A.C., Stihle, M., Umana, P., Benz, J.
Proc.Natl.Acad.Sci.USA
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