CATH Domain 3qi2B01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Guanine nucleotide-binding protein G(i) subunit alpha-1

Enzyme Information

UniProtKB Entries (1)

RGS14_HUMAN

Homo sapiens

Regulator of G-protein signaling 14

PDB Structure

PDB	3QI2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis Bosch, D.E., Willard, F.S., Ramanujam, R., Kimple, A.J., Willard, M.D., Naqvi, N.I., Siderovski, D.P. Plos Pathog.