CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.109 | NADH Oxidase |
|
3.40.109.10 | NADH Oxidase |
Domain Context
CATH Clusters
| Superfamily | NADH Oxidase |
| Functional Family |
Enzyme Information
| 1.5.1.38 |
FMN reductase (NADPH).
based on mapping to UniProt P39605
FMNH(2) + NADP(+) = FMN + NADPH.
-!- The enzymes from bioluminescent bacteria contain FMN, while the enzyme from Escherichia coli does not. -!- The enzyme often forms a two-component system with monooxygenases such as luciferase. -!- Unlike EC 1.5.1.39, this enzyme does not use NADH as acceptor. -!- While FMN is the preferred substrate, the enzyme can also use FAD and riboflavin with lower activity. -!- Formerly EC 1.5.1.29 and EC 1.6.8.1.
|
UniProtKB Entries (1)
| P39605 |
NFRA1_BACSU
Bacillus subtilis subsp. subtilis str. 168
FMN reductase (NADPH)
|
PDB Structure
| PDB | 3N2S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
NADH oxidase activity of Bacillus subtilis nitroreductase NfrA1: insight into its biological role.
Febs Lett.
|
