CATH Domain 3lpuA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family	POL polyprotein

Enzyme Information

UniProtKB Entries (1)

Q76353_9HIV1

Human immunodeficiency virus 1

Integrase

PDB Structure

PDB	3LPU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Christ, F., Voet, A., Marchand, A., Nicolet, S., Desimmie, B.A., Marchand, D., Bardiot, D., Van der Veken, N.J., Van Remoortel, B., Strelkov, S.V., De Maeyer, M., Chaltin, P., Debyser, Z. Nat.Chem.Biol.