CATH Domain 3iqhX02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1100

Domain Context

CATH Clusters

Superfamily	3.40.50.1100
Functional Family	Cysteine synthase

Enzyme Information

2.5.1.47

Cysteine synthase.

based on mapping to UniProt P45040

O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.

-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (1)

P45040

CYSK_HAEIN

Haemophilus influenzae Rd KW20

Cysteine synthase

PDB Structure

PDB	3IQH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature. Salsi, E., Bayden, A.S., Spyrakis, F., Amadasi, A., Campanini, B., Bettati, S., Dodatko, T., Cozzini, P., Kellogg, G.E., Cook, P.F., Roderick, S.L., Mozzarelli, A. J.Med.Chem.