CATH Domain 3hhkA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

Q99AU2_9HEPC

Hepatitis C virus subtype 1b

Genome polyprotein

PDB Structure

PDB	3HHK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase. Shaw, A.N., Tedesco, R., Bambal, R., Chai, D., Concha, N.O., Darcy, M.G., Dhanak, D., Duffy, K.J., Fitch, D.M., Gates, A., Johnston, V.K., Keenan, R.M., Lin-Goerke, J., Liu, N., Sarisky, R.T., Wiggall, K.J., Zimmerman, M.N. Bioorg.Med.Chem.Lett.