CATH Domain 3h3xA02

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.480	Cytochrome-c3 Hydrogenase; Chain A, domain 2
	4.10.480.10	Cytochrome-c3 hydrogenase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 hydrogenase, C-terminal domain
Functional Family

Enzyme Information

1.12.2.1

Cytochrome-c3 hydrogenase.

based on mapping to UniProt P18187

H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.

-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18187

PHNS_DESFR

Desulfovibrio fructosivorans

Periplasmic [NiFe] hydrogenase small subunit

PDB Structure

PDB	3H3X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Introduction of methionines in the gas channel makes [NiFe] hydrogenase aero-tolerant Dementin, S., Leroux, F., Cournac, L., de Lacey, A.L., Volbeda, A., Leger, C., Burlat, B., Martinez, N., Champ, S., Martin, L., Sanganas, O., Haumann, M., Fernandez, V.M., Guigliarelli, B., Fontecilla-Camps, J.C., Rousset, M. J.Am.Chem.Soc.