CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

2.6.1.102
GDP-perosamine synthase.
based on mapping to UniProt Q9A9H3
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro- 6-deoxy-alpha-D-mannose + L-glutamate.
-!- D-perosamine is one of several dideoxy sugars found in the O-specific polysaccharide of the lipopolysaccharide component of the outer membrane of Gram-negative bacteria. -!- The enzyme catalyzes the final step in GDP-perosamine synthesis.

UniProtKB Entries (1)

Q9A9H3
GDPPS_CAUVC
Caulobacter vibrioides CB15
GDP-perosamine synthase

PDB Structure

PDB 3BN1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
GDP-Perosamine Synthase: Structural Analysis and Production of a Novel Trideoxysugar
Cook, P.D., Holden, H.M.
Biochemistry
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