CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.1560 | putative 2-phosphosulfolactate phosphatase |
|
3.90.1560.10 | ComB-like |
Domain Context
CATH Clusters
| Superfamily | ComB-like |
| Functional Family |
Enzyme Information
| 3.1.3.71 |
2-phosphosulfolactate phosphatase.
based on mapping to UniProt Q5SID6
(2R)-2-phospho-3-sulfolactate + H(2)O = (2R)-3-sulfolactate + phosphate.
-!- The enzyme from Methanococcus jannaschii acts on both stereoisoimers of the substrate and also hydrolyzes a number of phosphate monoesters of (S)-2-hydroxycarboxylic acids, including 2-phosphomalate, 2-phospholactate and 2-phosphoglycolate. -!- This enzyme can also hydrolyze phosphate monoesters of (R)-2- hydroxycarboxylic acids such as (S)-2-phospho-3-sulfolactate and (R)- 2-phosphomalate, which, presumably, bind to the enzyme in opposite orientations.
|
UniProtKB Entries (1)
| Q5SID6 |
COMB_THET8
Thermus thermophilus HB8
Probable 2-phosphosulfolactate phosphatase
|
PDB Structure
| PDB | 2Z0J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of uncharacterized conserved protein from Thermus thermophilus HB8
To be Published
|
