CATH Domain 2yofA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Thymidylate kinase

Enzyme Information

UniProtKB Entries (1)

Q8I4S1_PLAF7

Plasmodium falciparum 3D7

Thymidylate kinase

PDB Structure

PDB	2YOF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Synthesis and Evaluation of Alpha-Thymidine Analogues as Novel Antimalarials. Cui, H., Carrero-Lerida, J., Silva, A.P.G., Whittingham, J.L., Brannigan, J.A., Ruiz-Perez, L.M., Read, K.D., Wilson, K.S., Gonzalez-Pacanowska, D., Gilbert, I.H. J.Med.Chem.