CATH Domain 2vzuA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.260	Galactose-binding domain-like

Domain Context

CATH Clusters

Superfamily	Galactose-binding domain-like
Functional Family

Enzyme Information

3.2.1.165

Exo-1,4-beta-D-glucosaminidase.

based on mapping to UniProt Q56F26

Hydrolysis of chitosan or chitosan oligosaccharides to remove successive D-glucosamine residues from the non-reducing termini.

-!- Chitosan is a partially or totally N-deacetylated chitin derivative that is found in the cell walls of some phytopathogenic fungi and comprises D-glucosamine residues with a variable content of GlcNAc residues. -!- Acts specifically on chitooligosaccharides and chitosan, having maximal activity on chitotetraose, chitopentaose and their corresponding alcohols. -!- Can degrade GlcN-GlcNAc but not GlcNAc-GlcNAc.

UniProtKB Entries (1)

Q56F26

EBDG_AMYOR

Amycolatopsis orientalis

Exo-beta-D-glucosaminidase

PDB Structure

PDB	2VZU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Structural Basis of Substrate Recognition in an Exo-Beta-D-Glucosaminidase Involved in Chitosan Hydrolysis. Lammerts Van Bueren, A., Ghinet, M.G., Gregg, K., Fleury, A., Brzezinski, R., Boraston, A.B. J.Mol.Biol.