CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
6 | Special |
|
6.10 | Helix non-globular |
|
6.10.250 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces |
|
6.10.250.2850 |
Domain Context
CATH Clusters
| Superfamily | 6.10.250.2850 |
| Functional Family |
Enzyme Information
| 4.2.1.101 |
Trans-feruloyl-CoA hydratase.
based on mapping to UniProt O69762
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA = feruloyl-CoA + H(2)O.
|
| 4.1.2.41 |
Vanillin synthase.
based on mapping to UniProt O69762
3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = vanillin + acetyl- CoA.
-!- Involved, together with EC 4.2.1.101 in the production of vanillin from trans-ferulic acid. -!- Vanillin is converted to vanillate by EC 1.2.1.67.
|
UniProtKB Entries (1)
| O69762 |
HCHL_PSEFL
Pseudomonas fluorescens
Hydroxycinnamoyl-CoA hydratase-lyase
|
PDB Structure
| PDB | 2VSS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A Ternary Complex of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) with Acetyl-Coa and Vanillin Gives Insights Into Substrate Specificity and Mechanism.
Biochem.J.
|
