CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.275 | Fumarase C; Chain B, domain 1 |
|
1.10.275.10 | Fumarase/aspartase (N-terminal domain) |
Domain Context
CATH Clusters
| Superfamily | Fumarase/aspartase (N-terminal domain) |
| Functional Family | Adenylosuccinate lyase |
Enzyme Information
| 4.3.2.2 |
Adenylosuccinate lyase.
based on mapping to UniProt P0AB89
(1) N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP. (2) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide.
-!- Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole.
|
UniProtKB Entries (1)
| P0AB89 |
PUR8_ECOLI
Escherichia coli K-12
Adenylosuccinate lyase
|
PDB Structure
| PDB | 2PTQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism.
J.Mol.Biol.
|
