CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.120 | Enolase-like C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Enolase-like C-terminal domain |
| Functional Family | L-talarate/galactarate dehydratase |
Enzyme Information
| 4.2.1.156 |
L-talarate dehydratase.
based on mapping to UniProt Q8ZL58
L-altarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
-!- The enzyme, isolated from the bacteria Salmonella typhimurium and Polaromonas sp. JS666, also has activity with galactarate (cf. EC 4.2.1.42).
|
| 4.2.1.42 |
Galactarate dehydratase.
based on mapping to UniProt Q8ZL58
Galactarate = (2R,3S)-2,3-dihydroxy-5-oxohexanedioate + H(2)O.
-!- The enzyme from the bacterium Escherichia coli is specific for galactarate, while the enzyme from Salmonella typhimurium also has activity with L-talarate (cf. EC 4.2.1.156). -!- Cf. EC 4.2.1.158.
|
UniProtKB Entries (1)
| Q8ZL58 |
TAGAD_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
L-talarate/galactarate dehydratase
|
PDB Structure
| PDB | 2PP3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry
|
