CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1370 | Aspartate/ornithine carbamoyltransferase |
Domain Context
CATH Clusters
| Superfamily | Aspartate/ornithine carbamoyltransferase |
| Functional Family | Ornithine carbamoyltransferase |
Enzyme Information
| 2.1.3.3 |
Ornithine carbamoyltransferase.
based on mapping to UniProt P04391
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.
|
UniProtKB Entries (1)
| P04391 |
OTC1_ECOLI
Escherichia coli K-12
Ornithine carbamoyltransferase subunit I
|
PDB Structure
| PDB | 2OTC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Substrate-induced conformational change in a trimeric ornithine transcarbamoylase.
Proc.Natl.Acad.Sci.USA
|
