CATH Domain 2o18A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.520	T-fold
	3.10.520.10	ApbE-like domains

Domain Context

CATH Clusters

Superfamily	ApbE-like domains
Functional Family	FAD:protein FMN transferase

Enzyme Information

2.7.1.180

FAD:protein FMN transferase.

based on mapping to UniProt P0AB85

FAD + [protein]-L-threonine = [protein]-FMN-L-threonine + AMP.

-!- The enzyme catalyzes the transfer of the FMN portion of FAD and its covalent binding to the hydroxyl group of an L-threonine residue in a target flavin-binding protein such as the B and C subunits of EC 7.2.1.1.

UniProtKB Entries (1)

P0AB85

APBE_ECOLI

Escherichia coli K-12

FAD:protein FMN transferase

PDB Structure

PDB	2O18
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure of a Thiamine biosynthesis lipoprotein apbE Seetharaman, J., Su, M., Wang, D., Fang, Y., Cunningham, K., Ma, L., Xiao, R., Liu, J., Baran, M.C., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L. To be Published