CATH Domain 2mjvB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 2

Enzyme Information

UniProtKB Entries (1)

TWST1_HUMAN

Homo sapiens

Twist-related protein 1

PDB Structure

PDB	2MJV
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer. Shi, J., Wang, Y., Zeng, L., Wu, Y., Deng, J., Zhang, Q., Lin, Y., Li, J., Kang, T., Tao, M., Rusinova, E., Zhang, G., Wang, C., Zhu, H., Yao, J., Zeng, Y.X., Evers, B.M., Zhou, M.M., Zhou, B.P. Cancer Cell