CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Functional Family | Crossover junction endonuclease MUS81 |
Enzyme Information
| 3.1.22.- |
Endodeoxyribonucleases producing other than 5'-phosphomonoesters.
based on mapping to UniProt Q96NY9
|
UniProtKB Entries (1)
| Q96NY9 |
MUS81_HUMAN
Homo sapiens
Crossover junction endonuclease MUS81
|
PDB Structure
| PDB | 2MC3 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
A winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexes.
Nucleic Acids Res.
|
