CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.30 | SH3 type barrels. |
|
2.30.30.850 |
Domain Context
CATH Clusters
| Superfamily | 2.30.30.850 |
| Functional Family |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P03355
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
| 3.1.-.- |
Acting on ester bonds.
based on mapping to UniProt P03355
|
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt P03355
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
| 2.7.7.- |
Nucleotidyltransferases.
based on mapping to UniProt P03355
|
| 3.4.23.- |
Aspartic endopeptidases.
based on mapping to UniProt P03355
|
| 2.7.7.49 |
RNA-directed DNA polymerase.
based on mapping to UniProt P03355
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a RNA or DNA primer. -!- DNA can also serve as template. -!- See also EC 2.7.7.7.
|
UniProtKB Entries (1)
| P03355 |
POL_MLVMS
Moloney murine leukemia virus isolate Shinnick
Gag-Pol polyprotein
|
PDB Structure
| PDB | 2M9U |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Nucleic Acids Res.
|
